The Effect of Variation of Collagen-Hydroxyapatite Synthesis Parameters on Compressive Strength using Taguchi Method

Wibawa, Tri and Fitri, Firdaus and Putro, Gunawan Madyono and Setiawan, Agris and Prijoto, Prijoto (2022) The Effect of Variation of Collagen-Hydroxyapatite Synthesis Parameters on Compressive Strength using Taguchi Method. In: 1st International Conference on Engineering Optimization and Management in Industrial Applications "Advancement of Optimization, Engineering Technology, and Management for Sustainable Environment", 29 Oct 2022, Yogyakarta.

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Abstract

Bone is a vital human organ that has many functions. One of the functions is as a buffer for the human body. In 2015, the rate of bone damage due to osteoporosis in Indonesia reached 19.7%. Meanwhile, in 2018 fracture sufferers in Indonesia reached 5.5% of the entire population of Indonesia. From the case above, the problem that arises is the increase in demand for a bone graft that exceeds capacity. Synthetic bone graft is the solution to this problem. Collagen-Hydroxyapatite is the main component in the manufacture of bone grafts. The results of the bone graft were tested for compressive strength, then tested for SEM-EDX-Mapping. The compressive strength test value obtained is processed using the Taguchi method to find how much influence the selected factors have. The compressive strength of the trabecular bone is the target value for this synthetic bone graft. Based on the research, the best compressive strength value in sample 1 is 0.176 MPa. While, the most influential factor on the compressive strength value is the ratio of collagen and hydroxyapatite, which has a percent contribution value of 6.8504%. The results of the SEM-EDX test showed that there were three components with the largest percentage, namely 35.27% carbon, 33.89% phosphorus oxide, and 24.03% calcium oxide.

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: : Bone graft, hydroxyapatite, collagen, compressive strength, taguchi method
Subjects: T Technology > T Technology (General)
Depositing User: ST, M.Sc Astrid Wahyu Adventri Wibowo
Date Deposited: 05 Jan 2023 06:40
Last Modified: 05 Jan 2023 06:41
URI: http://eprints.upnyk.ac.id/id/eprint/32198

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